5 Benefits Of Centrophenoxine Review (Dosage, Experience & More) 5/5 (2)

centrophenoxine review

Centrophenoxine is a cholinergic compound known for its positive effects on our cognition. But does this nootropic really work? Check out my full Centrophenoxine review.

Your inception recommends

It can improve your cognition & memory

Used by people with Alzheimer’s

Recommended (safe) daily dosage has been established

Your Inception does not recommend

Lack of data for long-term use

Centrophenoxine Review

Centrophenoxine is known as one of the first and original nootropics that can boost your cognition and memory.

The drug was developed in 1959, and it’s often sold under the brand name Lucidril and Meclofenoxate.

As with many other nootropics, this one has been often used among elders to treat dementia, while healthy people use it for enhancing cognitive performance. [1]



Compared to many other nootropics, we understand the working mechanism of centrophenoxine.

It contains two crucial chemicals: DMAE (Dimethyl-aminoethanol), which is a natural compound found in foods, and PCPA (Parachlor peroxyacetic acid), which is a monocarboxylic acid.

While the DMAE itself cannot cross the blood-brain barrier, it can do that within centrophenoxine.

As a result, this nootropic can increase your acetylcholine levels, increase glucose uptake, and protect neurons from oxidative stress.

Yes, centrophenoxine seems like a very potent nootropic.

But let’s try to understand all of the benefits we get from supplementing it.

Centrophenoxine Benefits

We already know that centrophenoxine provides a handful of benefits, but which benefits are scientifically proved and which not?

And what can we really expect from this nootropic?

Let’s find out.

centrophenoxine benefits

1. Centrophenoxine Can Improve Our Memory And Learning 

As I mentioned before, this nootropic is used among people with dementia because it can help with memory and learning. [2]

What’s better is the fact that studies show an improvement of long-term memory and alertness among healthy people as well [3].

While many nootropics only work on people with limited cognitive abilities, centrophenoxine seems like a big exception here.

But that’s not all.

2. Centrophenoxine Can Improve Our Mood

Initial studies show that supplementing centrophenoxine reduced anxiety in rats. [4]

If you combine this study with another one on 80 healthy subjects that were given DMAE for three months (and reported better mood, wellbeing, and more energy), we can conclude that this nootropic can improve our mood and overall wellbeing. [5]

But there is more…

3. Centrophenoxine Is Neuroprotective

I’m not sure if you knew that, but centrophenoxine can protect your nerve cells from damage.

I’ve come across studies on rats that were given centrophenoxine, which significantly improved their overall cognitive function, movement, and memory [6].

Do you wonder how is this possible?

Well, this nootropic can increase the activity of antioxidants, while it also improves brain energy.

Sounds like a win-win?

4. Centrophenoxine May Increase Our Lifespan

Another study done on mice showed that supplementing this drug increased the lifespan of mice by 30-40%, while it also reversed brain aging. [7]

If we will see similar effects on humans, it’s hard to say, but I hope more studies will be done soon.

5. Centrophenoxine May Help Treating Cancer

It’s far too early to talk about the effectiveness of centrophenoxine as a potential anti-cancer drug, but there is a promising study that proves that supplementing this drug can damage cancer cells. [8]

Centrophenoxine Side Effects

Centrophenoxine is a nootropic that has been used for ages, and it is considered to be safe.

Studies show that it is non-toxic for us. Therefore, you should not expect any side effects.

However, some people reported issues such as stomach pain, increased blood pressure, and irritability.

If you do experience any side effects, immediately consult your doctor.

centrophenoxine dosage

Centrophenoxine Dosage

If you want to avoid any adverse side effects, it’s essential to follow the recommended guidelines.

The recommended daily dose for younger people who want to enhance their cognition is 1 – 3 doses of 250 mg/day (so up to 750 mg/day).

My recommendation is to consult your doctor before supplementing centrophenoxine to be 100% sure it’s right for you.

Centrophenoxine Experience & Reviews

I’ve been personally taking centrophenoxine as a part of a bigger and more advanced nootropic stack.

I’ve been satisfied with this nootropic. However, I also wanted to see what others say about it.

After some research, I’ve found some real user feedbacks:

“This one works better than alpha-gpc or cdp-choline as a choline source. Nootropics Depot service and products are flawless as always. They are leaders in their market field.”

“I use this in a nootropic stack, and I believe its effects may take longer to make themselves apparent than in the short time period I’ve been using it. Reviewing the recommended dosage over 24 hrs, it’s likely that divided doses of 250 mg each are more efficacious than the single 500 mg dose I’ve been taking. I’m not aware of any side effects with this, or any other component of my nootropic mix.”

“Unlike many nootropics that are heavily hyped but seldom deliver the expected results Centrophenoxine actually works as advertised.”

centrophenoxine buy

Where To Buy Centrophenoxine?

If you’ve decided to start supplementing centrophenoxine nootropic and improve your cognition, you can order it here >>

This is definitely the most reliable online vendor for nootropics you can currently find.

If you want to take it as part of a more advanced nootropic stack, I do recommend supplementing Qualia Mind.

You can read more about it here >>

To get the lowest price possible, click here >>

Use code YOURINCEPTION for a special discount.

Your Inception Final Recommendation

Your Inception Guarantee

Your Inception recommends supplementing Centrophenoxine. 

Centrophenoxine looks like a very reliable nootropic that has been used for over 50 years now.

There are a lot of studies done that show a myriad of positive benefits of this smart nootropic.

The recommended daily dosage is well-established, and if you follow the rules, you can only expect positive benefits.

However, we still recommend consulting doctor, just to be sure.

Keep in mind that we do recommend cycling centrophenoxine: 5 days on and 2 days off.

Also, for the optimal performance, stacking this nootropic with other nootropics will provide better benefits.

Here you can check my most recommended nootropic stacks of all time >>



Frequently Asked Questions

1. What is Centrophenoxine half-life?
Centrophenoxine half-life is 2-4 hours. This means it takes up to 4 hours for half of the Centrophenoxine to disappear from our body.

2. Is Centrophenoxine a choline source?
Yes, Centrophenoxine is a choline source and can increase choline levels in our body.

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By |2019-08-14T14:52:17+00:00April 23rd, 2019|Categories: Nootropics|Tags: |2 Comments

About the Author:

Greg Gostincar is the founder of Your Inception. He has been researching, testing and experimenting with nootropics since 2015. Greg is one of the most recognized researchers in the field of nootropics.


  1. Murray Duffin August 10, 2019 at 3:45 pm - Reply

    Is centrophenoxine taken with or as an alternative to citicoline?

    • Greg Gostincar August 10, 2019 at 3:47 pm - Reply

      I’ve never mixed them, but I guess you could take both since they work differently.

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