2. Theobromine Benefits
Most of the benefits of using theobromine are associated with improved blood flow around the body. It acts as a vasodilator as well as an aid for urination and as a heart stimulant.
1. Theobromine Lowers Blood Pressure
Being a vasodilator, theobromine is considered helpful for regulating blood pressure. As it helps dilate blood vessels it improves the flow of blood in the area, thus reducing pressure in the vessels. At the same time, it also has diuretic properties boosting urine production. This activity helps lower blood volume.
One study investigated these effects by supplementing 979 mg of theobromine daily on 42 individuals with hypertension. Continuing with this dosage for three consecutive weeks, results revealed a significant reduction in blood pressure readings two hours following theobromine ingestion. Participants in the control group of the same study did not present this improvement. 
Likewise, a similar study compared the effects of theobromine and caffeine. Working with 24 otherwise healthy female participants the study looked at the effects of supplementing with 700 milligrams of theobromine as opposed to 700 milligrams theobromine taken along with 120 milligrams caffeine.
Findings showed that when ingested on its own, theobromine reduced blood pressure an hour after consumption. However, when taken alongside caffeine, the same blood pressure readings stayed consistent. 
Theobromine Side Effects
2. Theobromine Makes Tooth Enamel Stronger
This can seem counterintuitive as eating chocolate won’t offer this benefit. But using theobromine as a topical solution seems to help by increasing enamel hardness.
Some studies have shown that doing so can improve the surface hardness of human tooth enamel.  
This protective mechanism can also help protect against tooth decay which can otherwise cause cavities. There is also some indication that theobromine may well be more capable of fighting cavities than fluoride.
3. Theobromine Yields Mild Stimulant Effects
When administered dose-dependently, theobromine can raise heart rate while presenting stimulant effects on the body.
Some studies indicate that after ingestion, the alkaloid enhances concentration, focus, and visually processing information. 
4. Theobromine And Heart Health Benefits
New research regarding the heart health benefits of theobromine indicates that this compound may boost HDL levels independently.
One study tested the effects of theobromine on 152 healthy participants with participants consuming cocoa alongside 150 milligrams theobromine. A second group was given 850 milligrams of pure theobromine, while a third group received 1000 milligrams of theobromine alongside cocoa. The final group in the study was given a placebo.
The three groups other than the placebo group showed an increase in HDL levels suggesting that theobromine may be responsible for this increase. 
5. Theobromine Offers Mental Health Benefits
Given the vasodilatory effects of theobromine, it helps improve blood flow to the brain. This mechanism is an important marker for cognition. Some studies show that regular caffeine usage may restrict blood flow to the brain and reduce grey matter. However, certain nootropic compounds work by improving blood flow and oxygenation to the brain.
In this regard, theobromine can help by countering the vaso-restrictive properties of caffeine.
As a nootropic, many people use theobromine as a milder alternative to caffeine. Those who have used it claim to experience mental energy without the jitters associated with caffeine.
6. Theobromine Boosts Respiratory Health
Some evidence suggests that theobromine may broaden airways in the body and relax the body’s smooth muscle tissues, including tissue in the lungs. Such activity can help increase air passage to the lungs which may explain why this compound is, and was, considered an efficient cough suppressant.
One study out of Europe administered a chocolate- based medicine called ROCOCO to patients with a cough. Participants of the study were randomly assigned either ROCOCO or regular codeine. Those using the chocolate-based ROCOCO reported a significant improvement in symptoms within two days.
Researchers believe that cocoa has demulcent properties which can help relieve irritation and inflammation.  Using the chocolate-based medication showed that it was stickier and more viscous than standard cough medicine which protected nerve endings in the throat that trigger the urge to cough.
As theobromine opens up pathways for air to enter the lungs, it not only impacts coughing but also reduces the incidence of asthmatic episodes. 
7. Theobromine And Detoxification
The anti-inflammatory features in theobromine are due to its antioxidant activity which helps in limiting oxidative stress down to the cellular level.
By widening the blood vessels, theobromine promotes blood flow which reduces excess fluid collecting in the body. It gets removed from the body as urine allowing the blood to filter out and remove toxins.