Uridine Monophosphate Benefits
As uridine gets absorbed in the bloodstream, it can readily exert its nootropic effects in the following ways:
1. Improves Memory
Just as with anything else, uridine levels also decline with age. This has a direct effect on cognition, memory and recalls with brain cell membranes degenerating, neurotransmitter levels declining, taking neural and synaptic activity with them.
That said, memory is dependent to a large degree on neuroplasticity, or the brain’s ability to learn and form memories.
The process of turning experiences into memories depends on neurogenesis or the formation of new neurons.
The ability to think, deduce, and remember results from innumerable neurons and synapses connected together. Here uridine, in collaboration with DHA and choline, works to increase synapse density by encouraging the formation of neurons. 
Uridine, upon reaching the brain, enhances CDP-choline which is used for phosphatidylcholine synthesis. This process results in acetylcholine production which is a crucial neurotransmitter.
When you add more uridine to the diet it encourages the production of phospholipids through CDP-choline.
Now phospholipids are needed to encase fresh neurons upon formation. So, by promoting the growth of synapses, neurons, and neuroplasticity, uridine acts as a boost for cognitive performance.
The same also has the effect of increasing alertness and focus on individuals who may experience problems in these areas.
And while neuroplasticity is essential to all aspects of cognition, it has a particularly significant effect on memory.
Any loss can result in impaired cognition while increased neuroplasticity can become an important part of treating age-related conditions like Alzheimer’s.
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2. Neuroprotective Features
Uridine monophosphate offers many neuroprotective features. Apart from the obvious part, it plays in neurogenesis and synaptogenesis, UMP offers neuroprotection that is multilevel.
For starters, it protects the myelin sheath. Myelin is an important part of the central nervous system and crucial for optimal cognitive functioning.
The myelin sheath is a cover made of fats and proteins that insulates neurons enabling them to send signals faster and more efficiently. Cells known as Schwann cells produce the myelin sheath and any damage to these cells slows down neural communication.
Here, uridine protects the neuronal covering and helps treat any myelin sheath lesions. 
In addition, uridine can prevent fatty acid accumulation around neurons. If these acids start to collect in the brain, they can increase inflammatory responses.
They can also trigger free radical damage causing neural membrane breakdown.
Since uridine promotes neurotransmitter release, it can improve neural coordination.
It can help put the brain in a constant state of activity preventing decline from disuse. It can also inhibit oxidative stress by scavenging free radicals and fighting inflammatory responses.
Uridine Monophosphate Benefits
3. Activates Nerve Growth Factor
Nerve growth factor (NGF) is a protein important for the maintenance, survival, and growth of nerve cells including brain cells.
By optimizing the amount of NGF present, the body can upgrade its neural network and create stronger more abundant synaptic connections.
This, in turn, can help improve brain function including memory and cognition.
Uridine monophosphate has been known to promote neuronal growth by activating NGF through TrkA receptors. 
4. Improves Mood
Uridine also stimulates the release of the feel-good neurotransmitter dopamine in the brain. This is the chemical messenger responsible for sending signals to the brain.
The same is also involved in the sensations of reward and motivation.
A dopamine deficiency can often be the reason behind a lack of motivation, anxiousness, and lethargy among other things. And to help regulate or stabilize the mood, uridine might be the missing component here.
Since uridine improves the production of dopamine it can counter mood swings common in depressed patients.
Uridine can also successfully ward off stress by lowering the damaging effects of cortisol. 
The brain, being the sole organ for determining stress response, acts based on how much cortisol gets released.
However, cortisol can only be beneficial when it responds to acute stressors. But chronically high levels of cortisol only aggravate stress and increase the chance for depression instead.
In such cases, supplementing with uridine monophosphate can help counter that effect by promoting dopamine production.
Uridine gets transformed into a phospholipid in the brain and phospholipids are known to reduce the negative effects of cortisol. 
5. Reduces Depressive Symptoms
This mood-enhancing and especially depression-reducing facet of UMP is observed most when uridine monophosphate is stacked alongside omega 3 fatty acids such as DHA.
The antidepressant effects of omega 3s have already been established by extensive research. Uridine also seems to present a similar effect and a combination of the two was found to be effective at lower doses of each.
Researchers believe that depression is caused in part by an imbalance of neurotransmitters.
When uridine is paired with omega 3s, its effects are felt by changing fats in the brain. Their cumulative effect seems to make membranes more resilient that helps ease the flow of neurotransmitters.
In a highly cited 2011 study, uridine supplementation was seen to be effective for depression occurring in combination with bipolar disorder. 
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6. Anti-inflammatory Potential
The ability of uridine to attenuate inflammation is a protective function that extends beyond the brain. Not only is it beneficial to the brain but other body tissues as well. 
Typically, inflammation results from a direct reaction to tissue damage at a cellular level. This is actually a good thing for it is an attempt to repair the damage done and is beneficial in the short-term.
However, when inflammation becomes extended and persistent in the body, it brings about not only muscle damage but a number of other conditions as well.
Uridine acts as a leukocyte-adhesion inhibitor, a key factor in inflammatory responses. 
In one area, uridine’s anti-inflammatory effects were observed in carpal tunnel patients.
Participants received treatment using a combination of uridine, folic acid and vitamin b12 with results showing reduced pain and associated symptoms.