CILTEP is a brain supplement that was developed for optimizing brain performance. Unlike most of its competitors, CILTEP contains only five ingredients – two nootropics, two amino acids, and a vitamin. Is this enough for the benefits? And is it worth your money? Read my comprehensive CILTEP review.

ciltep review

What Is Neurofuel (CILTEP)?

CILTEP (now called Neurofuel) is a natural nootropic stack that was developed for better brain performance. Its formula may:

  • Enhance concentration and alertness
  • Improve mood
  • Increase motivation
  • Enhance ability to study
  • Improve memory formation
  • Improve brain function

CILTEP stands out due to a low amount of unique natural ingredients that you rarely see in other brain supplements. On the other hand, it lacks some scientifically-proven nootropics for brain health, which is quite shocking.

The name CILTEP (pronounced “siltep”) actually stands for “chemically induced long-term potentiation”. However, the brand Natural Stacks recently changed its name to Neurofuel. 

Natural Stacks is one of the world’s first open-source supplement companies with a strong mission to help people naturally achieve better brain performance and health.

And that’s the main reason why CILTEP is a product that brings a lot of attention.

However, CILTEP has an old-school formulation, and it lacks many nootropics. Does that mean it is not effective? Should you consider supplementing it?

CILTEP Ingredients

neurofuel ingredients
CILTEP nootropic has a 100% natural, open-source formula. Its formula is suitable for vegans, it is non-GMO, gluten-free, and paleo-friendly. This supplement has no proprietary blends, which is one major advantage.

Here is the list of all ingredients in CILTEP:

  • 900 mg Artichoke Leaf Extract
  • 20 mg Coleus Forskohlii Root Extract
  • 750 mg Acetyl-L-Carnitine
  • 5 mg Vitamin B6
  • 500 mg L-Phenylalanine

This CILTEP formula is based on taking three pills daily. 

Artichoke extract

Artichoke extract contains Luteolin, a natural inhibitor of PDE4. Studies have correlated lower levels of the enzyme PDE4 to significant increases in normal mental performance. [*] This includes cognitive enhancement, improved long-term memory, increased wakefulness, and neuroprotection.

Coleus Forskohlii Root Extract

Forskolin is derived from the plant Coleus forskohlii. Combined with Luteolin from Artichoke Extract, forskolin is theorized to synergistically increase the duration of cAMP in neurons. [*]

Forskolin is an effective compound that you need to cycle to avoid potential side effects. 

Vitamin B6

Vitamin B6 is an essential vitamin and a crucial enzymatic cofactor in normal metabolic and psychological function. Supplementing B6 may improve mood, reduce depression, and promote brain health. [*]


Acetyl-L-Carnitine is an amino acid that helps combat feelings of brain fog and fatigue. [*] It benefits people with depression and may help people with ADHD. L-Carnitine is a conditionally essential amino acid. 


L-Phenylalanine is a common amino acid that you can get plenty of from eating food rich in proteins. It is a building block of protein. Studies show that this amino acid may be beneficial for treating depression and skin disorders. Besides, it plays an important role in the synthesis of dopamine. [*]

There is no doubt that CILTEP is a well-dosed supplement. However, the lack of the most effective nootropics worried me a lot. That is why I decided to test it out and see if it is any good.

My Experience With Ciltep (Neurofuel)

I tested Ciltep (and later Neurofuel) on many occasions. In this review, I want to focus on the longest, 2-week test period of Neurofuel I recently conducted.


I started my test by taking 2 capsules of Neurofuel daily, and I took the capsules with food in the morning. I waited for about 1 hour to see if I noticed any effects. Sadly, nothing happened.


Despite the lack of effects on the first day, I continued taking 2 capsules daily for about 2 weeks. After about a week, I started noticing the first positive effects.


Neurofuel slightly boosted my focus, made me more alert and productive. 


Then I decided to increase the dosage to 3 capsules, which resulted in a slightly stronger boost, but it wasn’t a major difference. 


The effects were weak, especially compared to the competitors, but they were noticeable. I hoped to get stronger energy and mental boost, especially from a supplement with thousands of positive reviews. 


The reality is that ourtop-rated nootropics deliver a much more substantial brain boost, help me stay focused for a more extended period, and can enhance memory.

Neurofuel, on the other hand, is not nearly as effective, strong, and potent. But that doesn’t mean you should altogether avoid it.

How Does CILTEP Work?

CILTEP was designed to help you unleash your full potential. It has a very unique and simple formula that may provide multiple benefits. It was particularly made for people who need additional brainpower.

It is not a typical brain supplement for improving memory, but it was designed to offer full cognitive performance. Therefore, it may be beneficial for people with ADD and ADHD.

Let’s look at what exactly CILTEP does to our body.


cAMP Levels

The cAMP is a messenger that is important for many biological responses. One of its primary roles is to help neurons create better pathways in our brains. This can be naturally done by supplementing forskolin.

CILTEP contains Coleus Forskohlii herb that contains forskolin. By taking the recommended daily dosage, your body intakes 20 mg of forskolin.

Forskolin is the most potent nootropic in Ciltep and is responsible for many of its benefits. 

Brain Fog

Experts formulated CILTEP in a way that helps people achieve a higher state of concentration. By doing that, people often report that they have fewer issues with brain fog. 

However, based on my experience, Ciltep is less effective in helping with brain fog. When I tested it out on a day when I was tired and suffered from brain fog, I didn’t get any benefits. 

PD4E Production

PDE4 is a critical enzyme that is involved in the production of inflammatory mediators. This enzyme is best known for the correlation with the immune cells. You need some PDE4 to get rid of old unimportant memories. However, some people have too much and others too little. 

To boost your memory, you should limit PDE4. CILTEP contains quality Artichoke extract, which can help to inhibit the PDE4 formation. Again, this is important to have a great memory.

Taking CILTEP daily gives you 900 mg of Artichoke extract in your body, which is enough to achieve the desired effects.

Dopamine Production 

Dopamine is an organic chemical that works as a neurotransmitter and a hormone in our body. CILTEP can create a healthy balance of dopamine, which is essential for optimal focus and cognition. 

This nootropic stack contains L-Phenylalanine and vitamin B6, two essential nutrients for overall cognition. Among other benefits, they keep cAMP levels high. Also, they ensure a steady dopamine production.

Taking CILTEP pills daily may ensure you get enough energy, feel more alert, and improve your memory.


Let’s check which benefits you can expect from supplementing CILTEP.


On the Natural Stacks official website, you can read that supplement CILTEP may help people with ADHD. This is because CILTEP contains a dopamine precursor, which could increase dopamine levels in ADHD patients.

In addition, vitamin B6 deficiency is associated with ADHD symptoms.

There are some people with ADHD who claim that CILTEP helped them out. But others said that supplementing it didn’t do anything, so you need to try it out for yourself and see how it works on you.

Anxiety And Depression

One study showed that ALCAR, an ingredient in CILTEP, can decrease anxiety in people with minimal hepatic encephalopathy. [*] There are two other studies on animals that show similar effects.

We don’t know whether CILTEP as a supplement is effective for anxiety, but it shows some potential.

Another study showed that ALCAR might help with depression because it can increase serotonin levels. [*]

Keep in mind that CILTEP was not developed for anxiety and depression. As a matter of fact, there are more effective supplements available on the market.

Brain Fog And Cognition

Martin Jacobson is a famous poker player who stated that supplementing CILTEP helped him win the 2014 World Series Of Poker. Sadly, Natural Stacks sponsored him, so it is hard to take his statement seriously.

Based on my detailed research and experience, it is unlikely to expect that CILTEP would help people with brain fog.

On the other hand, it may slightly enhance cognition and increase mental sharpness. While it may also improve mental endurance, the effects were pretty weak during my test. 

Motivation And Energy

Some claim that CILTEP can boost your motivation. Since it is hard to measure that objectively, you need to rely on your subjective experience, and mine wasn’t the best. The biggest challenge is that no stimulants or stimulant-like nootropics in this supplement could boost energy levels and motivation. Because of that, you need to rely on your personal experience.

Recommended Dosage

Natural Stacks recommends taking 1-3 capsules of CILTEP on an empty stomach.

I recommend taking 3 capsules if you want to get any benefits from Ciltep. 1-2 capsules are just not enough due to its weak formulation.

There is no doubt that I noticed a slight difference whenever I took 3 capsules (compared to 1), but as I mentioned before, the effects were still pretty weak. 

Is It Safe?

There are no published clinical trials or studies on CILTEP, but according to my research, it is a safe dietary supplement if you follow the recommendations.

CILTEP is safe because it contains natural, well-researched compounds that are well-tolerated in our bodies. There are no risky synthetic compounds in this brain supplement.

I read lots of reviews, and side effects are rare. The most common side effects that people reported are:

  • Headaches
  • Nausea
  • Stomach pain

The best way to avoid side effects is to take CILTEP with food and to cycle it regularly. If you take it with food, you minimize the chances of nausea and stomach pain. And by periodically cycling it, you will avoid headaches.

Also, the effects of nootropics on developing brains are unknown, so I don’t recommend it to anyone under 18.

As a general precaution, I recommend consulting your healthcare practitioner before supplementing CILTEP. 

What Do Other Say About CILTEP?

To help you make up your mind about CILTEP, I searched for reviews on Amazon and other sites. Here is what people are saying about this supplement:

“I have been using CILTEP for years and it is without a doubt the best Nootropic I have used (and I have pretty much tried them all). I experiment with a lot of supplements so for me to buy something consistently it must work. I am working full time and attending grad school and CILTEP definitely helps my brain through those long days!” This stuff is incredible. It allows me to focus on projects like nothing I’ve ever taken. I suffer from mild ADHD, and this stuff is the bomb on helping me stay focused”

“I don’t believe this product makes any difference on me. I am still taking two pills a day on empty stomach as instructed. I didn’t feel anything different in terms claims on the description.”

“Not loving this product. Its been two weeks with zero effects. I take these as directed.”

As you can see, the reviews range from terrible to amazing. About 10-20% of people are dissatisfied with this supplement, and about 30% love it.

Where To Buy This Nootropic?

If you want to try CILTEP (Neurofuel), you can buy it here >>

CILTEP costs around $22.95 ($23.96 if you subscribe), which is quite affordable. The reason for such a low price is the number of ingredients in the supplement. Also, the supplement contains no branded ingredients, which are usually used in scientific studies and are more potent.

To get an  additional discount, use code YOURINCEPTION15. You will save up to 15% with this code!


Your Inception recommends supplementing Neurofuel. 

Neurofuel is a decent brain supplement for enhanced focus, deep concentration, and improved memory. It’s not the strongest nootropic supplement on the market, but it may work well for you.

However, if you are searching for the most potent stack, click on the link below.