CILTEP Review (Neurofuel): Is This Nootropic Still Worth It?

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• Fact Checked By: Spela Bednjanic, B.A. In Psychology

CILTEP is a brain supplement that was developed for optimizing brain performance. Unlike most of its competitors, CILTEP contains only five ingredients – two nootropics, two amino acids, and a vitamin. Is this enough for the benefits? And is it worth your money? Read my comprehensive CILTEP review.


Ciltep Review 

CILTEP (now called Neurofuel) is a natural nootropic stack that was developed for better brain performance. Its formula may:

  • Enhance concentration and alertness
  • Improve mood
  • Increase motivation
  • Enhance ability to study
  • Improve memory formation
  • Improve brain function

CILTEP stands out due to a low amount of unique natural ingredients that you rarely see in other nootropics. But, on the other hand, it lacks most scientifically-proven nootropics for brain health, which is quite shocking.

The name CILTEP (pronounced “siltep”) actually stands for “chemically induced long term potentiation”, which is quite unique. However, the brand Natural Stacks recently changed the name to NeuroFuel. 

It is one of many brain supplements of Natural Stacks company, one of the world’s first open-source supplement companies with a strong mission to help people naturally achieve better results. 

And that’s the main reason why CILTEP is a product that brings a lot of attention.

However, CILTEP has a very old formulation, and it lacks many nootropics. Does that mean it is not effective? Should you consider supplementing it?

CILTEP Ingredients

CILTEP nootropic has a 100% natural, open-source formula. Its formula is suitable for vegans, it is non-GMO, gluten-free, and paleo-friendly. There are no proprietary blends in this supplement, which is one major advantage.

Here is the list of all ingredients in CILTEP:

  • 900 mg Artichoke Leaf Extract
  • 20 mg Coleus Forskohlii Root Extract
  • 750 mg Acetyl-L-Carnitine
  • 5 mg Vitamin B6
  • 500 mg L-Phenylalanine

This CILTEP formula is based on taking three pills.

Artichoke extract

Artichoke extract contains Luteolin, a natural inhibitor of PDE4. Studies have correlated lower levels of the enzyme PDE4 to significant increases in normal mental performance. [*] This includes cognitive enhancement, improved long-term memory, increased wakefulness, and neuroprotection.

Coleus Forskohlii Root Extract

Forskolin is derived from the plant Coleus forskohlii. Combined with Luteolin from Artichoke Extract, forskolin is theorized to increase the duration of cAMP in neurons synergistically. [*]

Forskolin is an effective compound that you need to cycle to avoid potential side effects. 

Vitamin B6

Vitamin B6 is an essential vitamin and a crucial enzymatic cofactor in normal metabolic and psychological function. Supplementing B6 may improve mood, reduce depression, and even promote brain health. [*]


Acetyl-L-Carnitine is an amino acid that helps combat feelings of brain fog and fatigue. [*] It benefits people with depression, and it may help people with ADHD. L-Carnitine is a conditionally essential amino acid. 


L-Phenylalanine is a common amino acid that you can get plenty of from eating food rich in proteins. It is a building block of protein. Studies show that this amino acid may be beneficial for treating depression and skin disorders. Besides, it plays an important role in the synthesis of dopamine. [*]

There is no doubt that CILTEP is a well-dosed supplement. However, the lack of the most effective nootropics worried me a lot. That is why I decided to test it out and see if it is any good.

My Experience With Ciltep (Neurofuel)

I tested Ciltep (and later Neurofuel) on many occasions. In this review, I want to specifically focus on the longest, 2-week test period that I recently conducted.

When I first tested Ciltep, I was positively surprised by its effects. Of course, they were weak, but I could feel slightly more alert. Asa  result, I felt more motivated and productive.

Sadly, when I started comparing Ciltep to other nootropics, I understood the real value of Ciltep – and it isn’t really high.

While I got slightly improved concentration, I also expected an improved memory, which didn’t happen. 

I hoped to get more energy and mental clarity from CILTEP. I knew that some CILTEP claims about its power were a bit too optimistic, but I honestly expected slightly stronger benefits. For such a well-known and popular supplement with hundreds of positive reviews, I was slightly sad. 

My top-rated nootropics deliver a much stronger energy boost, help me stay focused for a longer period, and can enhance memory.

Ciltep, on the other hand, is not nearly as effective, strong, and potent. But that doesn’t mean you should altogether avoid it.


CILTEP was designed to help you unleash your full potential. It has a very unique and simple formula that may provide multiple benefits. It was particularly made for people who need additional brainpower.

It is not a typical brain supplement for improving memory, but it was designed to offer full cognitive performance. Therefore, it may be beneficial for people with ADD and ADHD.

Let’s have a look at what exactly does CILTEP does to our body.

Ciltep Dosage

cAMP Levels

The cAMP is a messenger that is important for many biological responses. One of its primary roles is to help neurons create better pathways in our brains. This can be naturally done by supplementing forskolin.

CILTEP contains Coleus Forskohlii herb that contains forskolin. By taking the recommended daily dosage, your body intakes 20 mg of forskolin.

Forskolin is the most potent nootropic in Ciltep and responsible for many of its benefits. 

Brain Fog

Experts formulated CILTEP in a way that helps people achieve a higher state of concentration. By doing that, people often report that they have fewer issues with brain fog. 

However, based on my experience, Ciltep is not effective in helping with brain fog. When I tested it out on a day when I was tired and suffered from brain fog, I didn’t get any benefits. 

PD4E Production

PDE4 is a critical enzyme that is involved in the production of inflammatory mediators. This enzyme is best known in the correlation with the immune cells. You need some PDE4 to get rid of old unimportant memories. However, some people have it too much and others too little. 

To boost your memory, you should limit PDE4. CILTEP contains quality Artichoke extract, which can help to inhibit the PDE4 formation. Again, this is important to have a great memory.

By taking CILTEP every day, you get 900 mg of Artichoke extract in your body, which is enough to achieve the desired effects.

Dopamine Production 

Dopamine is an organic chemical that works as a neurotransmitter and a hormone in our body. CILTEP can create a healthy balance of dopamine, which is essential for optimal focus and cognition. 

This nootropic stack contains L-Phenylalanine and vitamin B6, two essential nutrients for overall cognition. Among other benefits, they keep cAMP levels high. Also, they ensure a steady dopamine production.

Taking CILTEP pills every day may ensure you get enough energy, you feel more alert, and your memory improves.

CILTEP Benefits

Many people can expect the potential benefits of this nootropic supplement. Let’s check the benefits more in detail.


You can read on the Natural Stacks official website that supplement CILTEP may help people with ADHD. This is because CILTEP contains a dopamine precursor, which could increase dopamine levels in ADHD patients.

In addition, vitamin B6 deficiency is associated with ADHD symptoms.

There are some people with ADHD who claim that CILTEP helped them out. But there are also others who said that supplementing it didn’t do anything.

Anxiety & Depression

One study showed that ALCAR, an ingredient in CILTEP, can decrease anxiety in people with minimal hepatic encephalopathy. [*] There are two other studies on animals that show similar effects.

We don’t know whether CILTEP as a supplement is effective for anxiety, but it shows some potential.

Another study showed the ALCAR might help with depression because it can increase serotonin levels. [*]

Keep in mind that CILTEP was not developed for anxiety and depression. As a matter of fact, there are more effective supplements available on the market.

Brain Fog & Cognition

Martin Jacobson is a famous poker player who stated that supplementing CILTEP helped him win the 2014 World Series Of Poker. Sadly, Natural Stacks sponsored him, so it is hard to take his statement seriously.

Based on my detailed research and experience, it is unlikely to expect that CILTEP would help people with brain fog.

It may, on the other hand, slightly enhance cognition and increase mental sharpness. While it may improve mental endurance as well, the effects were pretty weak.

Motivation & Energy

Some claim that CILTEP can boost your motivation. Since it is hard to measure that objectively, you need to rely on your subjective experience, and mine wasn’t the best. The biggest challenge is that no stimulants or stimulant-like nootropics in this supplement could boost energy levels and motivation. Because of that, you need to rely on your personal experience. 

Some claim they feel more motivated and have more energy when they supplement CILTEP. Other people say that they don’t feel any effects. I believe it is hard to expect a strong energy or motivational boost from CILTEP.


Natural Stacks recommends taking 1-3 capsules of CILTEP on an empty stomach.

I recommend taking 3 capsules if you want to get any benefits from Ciltep. 1-2 capsules are just not enough due to its weak formulation.

There is no doubt that I noticed a slight difference whenever I took 3 capsules (compared to 1), but as I mentioned before, the effects were still pretty weak. 

I recommend consulting your healthcare practitioner before supplementing CILTEP. 


There are no published clinical trials or studies on CILTEP, but according to my research, it is a safe dietary supplement if you follow the recommendations.

CILTEP is safe because it contains natural, well-researched compounds that are well-tolerated in our bodies. There are no risky synthetic compounds in this brain supplement.

I read lots of reviews, and side effects are rare. The most common side effects that people reported are:

  • Headaches
  • Nausea
  • Stomach pain

The best way to avoid side effects is to take CILTEP with food and to cycle it regularly. If you take it with food, you minimize the chances of nausea and stomach pain. And by periodically cycling it, you will avoid headaches.

Also, the effects of nootropics on developing brains are unknown, so I don’t recommend it to anyone under 18.

CILTEP Reviews

To help you make your mind about CILTEP, I searched for reviews on Amazon and other sites. Here is what people are saying about this supplement:

“I have been using CILTEP for years and it is without a doubt the best Nootropic I have used (and I have pretty much tried them all). I experiment with a lot of supplements so for me to buy something consistently it must work. I am working full time and attending grad school and CILTEP definitely helps my brain through those long days!” This stuff is incredible. It allows me to focus on projects like nothing I’ve ever taken. I suffer from mild ADHD, and this stuff is the bomb on helping me stay focused”

“I don’t believe this product makes any difference on me. I am still taking two pills a day on empty stomach as instructed. I didn’t feel anything different in terms claims on the description.”

“Not loving this product. Its been two weeks with zero effects. I take these as directed.”

As you can see, the reviews range from terrible to amazing. About 10-20% of people are dissatisfied with this supplement, and about 30% of people love it.

Where To Buy CILTEP Nootropic?

If you want to try CILTEP (Neurofuel), you can buy it here >>

CILTEP costs around $29.95, which is quite affordable. The reason for such a low price is the number of ingredients in the supplement. Also, the supplement contains no branded ingredients, which are usually used in scientific studies and are more potent.

To get a special discount, use code YOURINCEPTION15. You will save up to 15% with this code!


Your Inception does not recommend supplementing CILTEP. Based on our detailed review, CILTEP used to be one of the best and most popular nootropic stacks for mental health on the market. Sadly, competition has arrived and developed much better nootropic stacks.

Since 2019, we no longer recommend it. But don’t understand us wrong; CILTEP is not a bad supplement -there are just better alternatives available.

Click on the button below to check them out.