Qualia Mind Review: Still The Best Nootropic Supplement?

Written By • Last Update:

• Fact Checked By: Spela Bednjanic, B.A. In Psychology

Qualia Mind is a nootropic supplement that can enhance cognition. It contains 28 nootropic compounds, making it one of the most advanced brain supplements. But is it effective? How about its safety? Here is an in-depth Qualia Mind review.

What Is Qualia Mind?

qualia mind review

Qualia Mind is a nootropic stack developed for achieving optimal mental performance. It is classified as a dietary supplement despite its complex formulation and 28 active ingredients.

Nootropics are brain-enhancing compounds that are side-effects free. Most nootropic supplements contain a blend of individual nootropic compounds.

Qualia Mind is one of the most trusted nootropic blends on the market. It was developed to:

  1. Improve brain fog
  2. Provide energy & focus
  3. Boost brain nutrition and brain function
  4. Increase focus
  5. Help with mental clarity and flow
  6. Support sustained mental focus

Qualia Mind is one of the few dietary supplements that was used in a clinical study in 2020. A randomized, double-blind, placebo-controlled, crossover study was conducted to check the efficacy of Qualia Mind on cognition in a healthy population.

This clinical study showed that Qualia Mind improved cognitive function in healthy individuals. However, this clinical trial is still ongoing to evaluate the safety and efficacy of Qualia Mind.

Because of this and other reasons, Neurohacker Collective, the company behind the product, has an outstanding reputation in the nootropic industry. They developed more than six other advanced supplements for sleep, immunity, longevity, and energy besides Qualia Mind.

Qualia Mind is one of the most expensive and complex nootropic stacks, but it is also one of the most trusted and popular. Can you expect an improvement by supplementing it? And is it safe?

Let’s dive into what makes Qualia Mind stand out.

Qualia Mind Ingredients

Qualia Mind is a premium supplement that contains 28 active ingredients. Its complex formula makes Qualia Mind such a distinctive product on the market.

Here are ingredients in Qualia Mind:

  • 100 mg  Vitamin C
  • 25 mcg Vitamin D3
  • 100 mg Thiamin B1
  • 50 mg Niacin B3
  • 20 mg Vitamin B6
  • 1000 mcg Vitamin B12
  • 50 mg of Panthotenic acid
  • 500 mg Acetyl-L-Carnitine
  • 500 mg Artichoke stern and leaf extract
  • 300 mg Bacopa monnieri
  • 300 mg Rhodiola rosea root
  • 300 mg DL-Phenylalanine
  • 250 mg Uridine Monophosphate Disodium
  • 250 mg N-Acetyl-L-Tyrosine
  • 200 mg Taurine
  • 200 mg L-Theanine
  • 200 mg Alpha GPC
  • 150 mg Cognizin
  • 100 mg Mucuna pruriens seed
  • 100 mg Phosphatidylserine
  • 100 mg Theobromine
  • 90 mg Caffeine
  • 80 mg DHA
  • 60 mg Celastrus paniculatus seed extract
  • 50 mg Ginkgo biloba
  • 20 mg Coleus forskohlii root
  • 10 mg Pyrroloquinoline quinone
  • 50 mcg Huperzine A

Neurohacker Collective is known for combining lots of nootropics in such advanced blends. But what exactly can those nootropics do? Are they even safe and effective at the dosages you can find in Qualia Mind?

Qualia Mind Ingredients

Acetyl-L-Carnitine HCL

Acetyl-L-carnitine is an amino acid produced by the body from methionine and lysine. It is involved in the mitochondrial oxidation of long-chain fatty acids. [*]

Supplementing Acetyl-L-carnitine may be beneficial for depression and fatigue. [*][*]

Qualia Mind contains 500 mg, which is an optimal dosage.

Artichoke Stem and Leaf Extract (5% Cynarin)

Artichoke leaf extract (Cynara scolymus) has antioxidant benefits for brain health and brain function. [*] Besides, using it reduces cholesterol and improves fat digestion. [*] Artichoke may also boost blood flow to the brain. [*]

Artichoke is not a typical nootropic, but it shows some nootropic benefits.

Bacopa Monnieri Leaf Extract (45% Bacosides)

Bacopa monnieri (Brahmi) is an adaptogen herb used in traditional Ayurveda medicine. [*] Bacopa is one of the most potent nootropics for improving short-term memory. [*] It also decreases stress and anxiety. It may provide anti-inflammatory effects. [*][*]

Bacopa Monnieri is a prevalent adaptogen herb known for its cognitive-boosting properties. [*]

The most important benefit of this Ayurvedic herb is its effect on memory. Randomized, double-blind, placebo-controlled trials showed the memory benefits of Brahmi. [*]

The recommended daily dosage is 300 mg of a potent extract with 50% of the active compound bacosides. That’s precisely the dosage in Qualia Mind.

Rhodiola Rosea Root Extract (3% Rosavins, 1% Salidrosides)

Rhodiola Rosea is an adaptogen herb known for its anti-fatigue and adaptogenic properties. [*] Rhodiola Rosea enhances well-being and cognition in healthy individuals. [*] It is also beneficial for depression and anxiety. [*]

The recommended daily dosage is 50-688 mg of a quality extract with 3% rosavins and 1% salidrosides. Qualia Mind has 300 mg of Rhodiola.


DL-Phenylalanine is an amino acid that improves mood and anxiety levels. [*] It has been studied for its effects on depression as well.

Phenylalanine is crucial for the production of tyrosine (dopamine precursor), dopamine, and epinephrine. [*]

One study shows that phenylalanine can help with treating depression. [*] Other studies show mixed results.

Uridine Monophosphate Disodium

Uridine 5 monophosphate heptahydrate is a nucleotide that possesses cognitive enhancing properties. [*] Studies show reduced depressive symptoms in patients with bipolar disorder. [*]

However, we lack studies on healthy individuals. The recommended daily dosage of uridine monophosphate disodium has not been established yet.

N-Acetyl L-Tyrosine

L-Tyrosine is an amino acid known for its cognitive and physical boosting properties. It also increases the production of dopamine, which is important for attention span. [*]

N-Acetyl L-Tyrosine is trendy among athletes, entrepreneurs, and students, because it improves cognitive function in stressful situations. [*] For the best effects, it is essential to supplement it before a stressful activity.  [*]

Studies show that supplementing NALT enhances cognition in animals and adults. Supplementing NALT is beneficial for people with ADHD [*], and it promotes cognitive flexibility in healthy adults. [*]

The recommended daily dosage is 500-2000 mg. Qualia Mind has 250 mg.


Taurine is an organic acid that is important for cardiovascular function and brain development. [*] Just two weeks of taurine supplementation improved blood flow and reversed endothelial dysfunction in type 1 diabetics. [*]

Dosage between 500 mg and 2000 mg have been proven effective.


L-theanine is an amino acid found in green that promotes relaxed focus. It calms people down while it increases focus and cognitive performance. [*] L-theanine increases blood flow and the production of neurotransmitters. Supplementing L-theanine increases alpha-wave activity in the brain. [*][*]

The recommended daily dosage is 100-200 mg. Qualia Mind has 200 mg of L-theanine.

Alpha GPC

Alpha GPC (Alpha-glycerophosphocholine) is a cholinergic compound that increases the amount of acetylcholine in our brain. [*] Acetylcholine is a neurotransmitter responsible for learning, focus, and memory.

Studies show that supplementing Alpha GPC may slow down cognitive decline and improve power output in adults. [*]

The recommended daily dosage is 300-600 mg. You can find 200 mg in Qualia Mind.

Citicoline (Cognizin®)

Citicoline is the generic name for CDP-choline or cytidine diphosphate choline. It is a building block of cell membranes and affects the brain’s ability to produce acetylcholine. [*]

Citicoline improves memory, circulation and protects the brain from harmful agents. [*][*]

Long term, it helps maintain healthy brain function against age-related structural changes and mental decline. Citicoline has also been suggested to assist with recovery after brain injury.

Mucuna Pruriens Seed Extract (50% L-Dopa)

Mucuna pruriens (velvet bean) is a legume used in traditional Ayurvedic and Unani medicines. The bean contains an amino acid L-DOPA, which is a direct dopamine precursor. [*] Supplementing Mucuna pruriens supports dopamine, norepinephrine, and serotonin production. [*]

It also supports healthy stress hormone levels, neuroprotection, and growth hormone levels. [*] In this study, an increase in well-being has been found secondary to a reduction of cortisol.

Phosphatidylserine (Sharp-PS® Green)

Phosphatidylserine is a compound similar to a dietary fat found in human neural tissue. Supplementing phosphatidylserine contributes to cognitive functioning, slows down cognitive decline, and improves memory. [*]

Since phosphatidylserine levels naturally decline with aging, supplementing it is beneficial.

One study shows that 300 mg of phosphatidylserine for 12 weeks significantly reduced symptoms of cognitive decline in persons with Alzheimer’s disease. [*]

In another study, people were given 300 mg of phosphatidylserine for 6 months. The scores on the rating scales associated with cognitive decline and dementia improved. [*]

The recommended daily dosage is 100 mg, taken up to 3 times. Qualia Mind contains 100 mg.


Theobromine is a compound that has stimulatory effects similar to caffeine. [*] Over 20 studies show that theobromine increases blood flow in healthy adults. [*] It has a stimulatory effect, but it is weaker than caffeine.

Anhydrous Caffeine (Whole Coffee Fruit Extract From Organic Coffeeberry)

Caffeine is a powerful stimulant that improves energy, physical strength, and endurance. [*] It enhances performance and ensures prolonged wakefulness. [*] It may also improve the well-being of individuals.

Habitual caffeine use is associated with a reduced risk of Alzheimer’s and liver cancer. Anhydrous caffeine is extracted from the whole coffee fruit, and it is extremely potent. That’s why it has such strong stimulant properties.

DHA (Docosahexaenoic Acid from Algae)

DHA is an anti-inflammatory fatty substance and a must-use compound for optimal brain health. [*] Studies show that supplementing DHA improves ADHD, fights inflammation, helps with eye health, and may slow down cognitive decline. [*]

The combination of DHA and EPA is crucial for the working nervous system.

Celastrus Paniculatus Extract

Celastrus paniculatus is a plant that has been used in traditional Ayurveda medicine to alleviate cognitive issues and promote intestinal health. [*]

Animal studies show that it may be beneficial for improving cognitive performance under stress. [*][*]

We lack clinical studies to confirm its safety and efficacy in healthy individuals. 

Ginkgo Biloba Leaf Extract (24%)

Ginkgo biloba is a popular herb used by the elderly to slow down cognitive decline. [*] Multiple studies confirm that supplementing Ginkgo improves cognitive and neuropsychiatric symptoms in persons with dementia. [*] Ginkgo can also improve cognition and age-related memory loss. [*]

The recommended daily dosage is 120-240 mg. Qualia Mind has 50 mg.

Coleus Forskohlii Root Extract (20% Forskolin)

Coleus Forskohlii is a herb used in traditional Ayurvedic medicine for boosting testosterone. [*] Its main bioactive ingredient, forskolin, may work as a fat burner. Other benefits include reduced fatigue, increased HDL, and improved inflammation.

Pyrroloquinoline Quinone

Pyrroloquinoline Quinone Disodium (PQQ) is a vitamin-like molecule that improves stress, sleep, and fatigue levels while also offering significant antioxidant protection. [*] Supplementing pyrroloquinoline Quinone leads to reduced stress, fatigue, and improved sleep. [*]

The recommended daily dosage is 20-40 mg.

Huperzine A (Huperzia Serrata Leaf Extract)

Huperzine A is a cognitive enhancer extract from the Huperzia Serrata herb that inhibits an enzyme that degrades the learning neurotransmitter, acetylcholine. [*]

Supplementing Huperzine A may improve memory and slow down cognitive decline. [*]

Due to its effects on neurotransmitters, you need to cycle Huperzine-A to avoid potential side effects.


Besides the nootropics, Qualia Mind contains crucial vitamins for brain health.

  • Vitamin C
  • Vitamin D3
  • Thiamine
  • Niacin
  • Vitamin B6
  • Vitamin B12
  • Pantothenic acid (Vitamin B5)

So, which benefits can you expect from Qualia Mind?

Qualia Mind Benefits

Benefits of Qualia Mind include:

  • Better focus and concentration
  • Long-term brain health
  • Enhanced memory & cognition
  • Improved productivity
  • Mental clarity
  • Amplified drive & energy boost

Better Focus And Concentration

The first and most important benefit of Qualia Mind is increased focus and concentration. A mix of potent nootropics ensures that you get more focused, even during stressful activities. Sustaining attention is essential if you want to stay in the zone (flow).

Qualia Mind can improve your focus and concentration by increasing the amount of three crucial neurotransmitters – dopamine, acetylcholine, and noradrenaline.

Better Memory

Nootropics like Bacopa Monnieri, Ginkgo Biloba, Alpha GPC, and Cognizin are known memory boosters. They can improve different types of memory in healthy individuals. Having a great memory is crucial for all active individuals, and Qualia Mind excels here.

Long-Term Brain Health

Qualia Mind contains potent anti-oxidant nootropics and vitamins that protect your brain from toxins and stress. In addition, certain compounds also protect your nerve cells. Qualia Mind is an outstanding supplement for people who care about their brain health.

Energy Boost

Because of the combination of caffeine, PQQ, theobromine, and l-theanine, you can expect a mild energy boost from Qualia Mind. Compared to drinking coffee, the boost is weaker, but it lasts longer and comes without side effects such as nervousness.

Many prefer the energy boost from dietary supplements to drinking coffee.

Improved Learning

Despite its high price, Qualia Mind is popular among students as well. Learning with this supplement is easier and more effective. You can stay in the flow for about 4-5 hours without any significant side effects.

But how exactly does Qualia Mind work?

How Does Qualia Mind Work?

Qualia Mind is based on complex systems science. It upregulates multiple pathways, takes advantage of nutrient synergies, and it embraces the Goldilocks zone. Some Qualia Mind compounds provide immediate physiological and neurochemical effects, while others provide long term effects by:

  • Supporting mitochondrial function
  • Supporting acetylcholine signaling
  • Neuron synaptic formation

All in all, Qualia Mind enhances BDNF (brain-derived neurotrophic factor), supports neuron & synaptic function, supports neurotransmitter signaling, and enhances stress resilience.

But is it safe for supplementation?

Qualia Mind Side Effects

Most ingredients in Qualia Mind are considered safe for supplementation. The dosages of all ingredients, quality extracts, and high-production standards make Qualia Mind a safe supplement for supplementation.

However, some Qualia Mind nootropics may still cause adverse side effects. In particular, Huperzine A is a problematic ingredient when taken long-term for more than six months. Huperzine A side effects may include: [*][*]

  • Nausea
  • Diarrhea
  • Dry mouth
  • Constipation
  • Vomiting
  • Fainting
  • Restlessness
  • Cramping
  • Loss of appetite
  • Dizziness
  • Blurred vision
  • Sweating
  • Inability to sleep
  • High blood pressure
  • Slowed heart rate

Another problematic compound is caffeine, which can cause restlessness, insomnia, headaches, anxiety, dehydration, and rapid heart rhythm. [*]

Lastly, supplementing Gingko bloba can lead to moderate adverse effects: [*]

  • Nausea
  • Muscle weakness
  • Digestive problems
  • Diarrhea
  • Allergic skin reactions
  • Headaches

Qualia Mind Warnings

Qualia Mind contains ingredients that can interact with certain medications:

  • Antidepressants;
  • Anticoagulants and antiplatelet medications, including Clopidogrel (Plavix), aspirin, Ibuprofen (Advil, Motrin), Diclofenac (Voltaren, Cataflam), Naproxen (Anaprox, Naprosyn), Enoxaparin (Lovenox), Dalteparin (Fragmin), Heparin, and Warfarin (Coumadin).
  • Antibiotics, including Enoxacin (Penetrex), Ciprofloxacin (Cipro), Sparfloxacin (Zagam), Norfloxacin (Chibroxin, Noroxin), Grepafloxacin (Raxar), and Trovafloxacin (Trovan);
  • Drying medications (anticholinergics) including Atropine and Scopolamine;
  • Ephedrine and other stimulants that speed up the nervous system;
  • Medications for Alzheimer’s disease (Acetylcholinesterase (AChE) inhibitors);
  • Medications used for allergies (antihistamines);
  • Medications for high blood pressure, including Verapamil (Calan, Isoptin, Verelan), Nifedipine (Adalat, Procardia), Isradipine (DynaCirc), Felodipine (Plendil), Diltiazem (Cardizem), and Amlodipine (Norvasc);
  • Medications that increase blood flow to the heart.

If you take any of the mentioned drugs, consult your doctor before supplementing Qualia Mind to avoid potential risks.

Suggested Use & Dosage

According to Neurohacker Collective, take five to seven capsules with water first thing in the morning before eating.

If an upset stomach occurs, take them with breakfast instead. Optimal dosage can vary based on body weight and sensitivity.

Don’t take more than ten capsules at once and more than twelve in a day. Do not exaggerate with the daily dosage, but feel free to experiment a bit.

Qualia Mind Reviews

This powerful nootropic stack is used and recommended by several well-known doctors, health, and fitness experts such as:

Mark Divine (Sealift), Ben Greenfield (Ben Greenfield Fitness), Dr. Scott Barry Kaufman (The Psychology Podcast), and Rachelle Brooke Smith (Disruptive Dare).

What do customers say about Qualia Mind?

“Qualia is remarkable. Clarity, focus, and fluidity of thought. Like those 45 mins after a perfect cup of coffee, expect it lasts for 6 hours and you never crash. Alertness and empathy increase, which leads to a kind of openness of expeirence and more balanced and timely judgments.”

“I love Qualia. It’s definitely worth the money. I rarely write reviews but this one was worth it. It’s my honest Qualia review. Love it!”

“I have been taking Qualia for almost 1 month and I can truly say that I’ve noticed a positive difference in my clarity, focus, attention, and mental energy…particularly in the morning. I look forward to experiencing other neurocognitive changes as I continue to incorporate this supplement into my routine.”


How does Qualia Mind compare to other top-rated nootropic supplements? You can check the comparisons here:

Qualia Mind vs. Modafinil

How can you compare the most advanced brain supplement to the most popular smart drug Modafinil

Qualia Mind is a dietary supplement that optimizes your brain performance through various mechanisms. It is safe, generally side-effects free, and made for long-term supplementation. Its effects are strong and can help people optimize their mental health.

Modafinil, on the other hand, is a prescription drug used for treating sleep-related issues. Modafinil can boost your energy levels, but it is not a nootropic. Long-term use can cause severe health issues and side effects. Also, Modafinil has almost no nootropic effects.

Due to that, there is no doubt Qualia Mind is the better choice between the two. 

Qualia Mind vs. Qualia Mind Caffeine-Free

Neurohacker Collective also developed a caffeine-free version of Qualia Mind. The reason for that is that many people avoid caffeine due to its adverse effects. In addition, adding caffeine to such a potent nootropic supplement may be a bit too much for some people.

The caffeine-free version also contains no theobromine, another stimulant. Both products are amazing, but for long-term health, the caffeine-free version is even better because it doesn’t contain stimulants that could cause mild side effects. 

For short-term use, Qualia Mind with caffeine is more potent and provides stronger benefits.

Where To Buy Qualia Mind?

Qualia Mind is available for purchase in online stores such as Amazon, eBay, LuckyVitamin, Walgreens, and Livehelfi. 

The best place to buy Qualia Mind is at the Neurohacker Collective store. 

Click here to check its latest price >>

Use discount code YOURINCEPTION to receive a 15% discount. 

Qualia Mind Price

One botle of Qualia Mind with 154 capsules costs $139. If you subscribe, you will save 50% on the first order and pay only $69.50. The next shipments will cost you $119. 

154 capsules are enough for 28 days of supplementation. 


Qualia Mind is the most advanced nootropic supplement currently on the market. It contains 28 nootropic compounds that provide multiple cognitive benefits. 

However, Qualia Mind is among the most expensive brain supplements. It also contains a few compounds that could cause adverse side effects. 

Qualia Mind is a premium supplement designed for high-achievers who want to boost their brain performance and improve mental agility. If you can afford it, we highly recommend supplementing it. 

Frequently Asked Questions

1. When Should You Take Qualia Mind?

You should take it in the morning with food. Avoid taking Qualia Mind in the afternoon because it contains stimulants that can impact your sleep. 

2. What Is The Difference Between Qualia Mind And Qualia Focus?

Qualia Mind is the more complex and advanced version of Qualia Focus. Qualia Mind contains 28 nootropics, while Qualia Focus contains 24. Qualia Mind is also more expensive than Qualia Focus.

3. Is Qualia A Scam?

No, Qualia supplements are not a scam. Just the contrary, Qualia is one of the best nootropics on the market.

4. Does Qualia Mind Work Immediately?

Qualia Mind is an effective supplement that can improve the brain’s ability, reduce brain fog, have strong cognitive effects in just 30-45 minutes after supplementation. 

5. How Safe Is Qualia Mind?

Qualia Mind is considered safe when taken properly. It is recommended to take five to seven capsules a day for 28 days, then take a few days off. You need to consult your doctor if you take any medications prior to the supplementation of Qualia Mind. 

6. Is Qualia Mind A Stimulant?

Qualia Mind is not a stimulant but a nootropic supplement. However, Qualia contains stimulants like theobromine and caffeine to boost your energy and brain performance. To avoid side effects, take it with food in the morning. 



Leave a Comment