Smart drugs are getting very popular among students, entrepreneurs, managers, and other high achievers. If you are interested in smart drugs, here is the ultimate smart drugs list.

Why Having A Nootropic Drugs List?

We’ve been researching nootropics and smart drugs for several years. In the beginning, most people thought that smart drugs are nootropics. And vice versa. Today, we know there is a significant difference between both groups.

There are still many “experts” that don’t differentiate or that they intentionally talk about smart drugs as nootropics. We still don’t get it why they have been doing it, but anyhow, that’s part of the game, we guess.

As a result, we still receive tons of questions each month about which “nootropic” is better – Modafinil or Adderall. That’s wrong for several reasons, but let’s instead focus on why having such a list is useful for you.

Based on our research, most people avoid smart drugs due to potential side effects, their partly illegal status, and lack of research. However, you can find some people that still love to take smart drugs. We used to like them as well.

But when we started researching them, it was tough to understand the difference. Since there is not a clear distinction between nootropics and smart drugs, we’ve decided to create a separate list for both groups. That’s the way to make this distinction as clear as possible.

If you are more interested in nootropics, then check our nootropics listBut if you want to find more about the benefits of specific smart drugs, then continue reading this post.

What we’ve done for you is that we gathered the most popular and commonly used smart drugs that you can currently find on the market. As we said before, some of them are illegal in certain countries, you might need a prescription for others, and you might be able to find some of them online.

Whatever the reason for your interest, please promise you will do thorough research before you try any smart drugs. We’d really appreciate that.

So, here is our promised list.

List Of Nootropics Smart Drugs


Adderall is a drug that is used for treating ADHD (Attention Deficit Hyperactivity Disorder) and narcolepsy. [1] This smart drug is made of amphetamine salts and has been proven to provide the promised benefits. [2]

In addition, Adderall is often used for enhancing cognitive and physical performance. A meta-analysis of clinical trials found that supplementing Adderall can improve working memory, attention, and episodic memory. It can also provide performance-enhancing effects. [2]


Adrafinil is is another drug that works as a precursor to Modafinil, another popular “supplement” on our list. This is a stimulant that changes into Modafinil in our body. [3]

It is used for increasing alertness, wakefulness, positive mood, and attention.  This compound is especially popular among night workers. [4] Do not take it in the afternoon, because it can impair your sleep. Also, keep in mind that WADA banned it. 

If you want to learn more, then click here: Adrafinil 

Aricept (Donepezil)

Donepezil is a drug used to treat Alzheimer’s diseases. It works by increasing the levels of acetylcholine in our brains. [5] Despite the lack of studies, this drug may improve cognitive function in healthy individuals. [6]


Centrophenoxine (also known as Lucidril and Mexlofenoxate) is a prescription drug and a dietary supplement in some countries. Studies show that supplementing this compound can improve memory in the elderly. [7] It seems especially effective in reversing aging and cognitive decline. [8]


L-Deprenyl (also called Selegiline) is a medication used to treat Parkinson’s disease and depressive disorders. It is also used as a drug for treating ADHD. [9] This may be the reason healthy individuals use it for improving cognitive performance. 

This compound interacts with a huge variety of drugs and comes with many side effects, so be careful!

Modafinil (Provigil)

Modafinil is probably the most popular smart drug on our list. It is used for treating sleep apnea, narcolepsy, and other sleep-related issues. [10] Due to not being very addictive, it is often used among CEOs, managers, and other high-achievers.

Healthy people report being more focused, alert and have more energy when they supplement it.

You can read about our experience here: Modafinil 


Last but not least is Ritalin, also named Methylphenidate. This is another CMS stimulant used to treat narcolepsy and ADHD. [11] Studies show that supplementing Ritalin may improve memory in healthy adults. Also, it can improve overall brain function; that’s why students and highly-active individuals often use this drug. [12]

Why Are They Problematic?

There are many reasons why you should avoid smart drugs. To mention a few:

  1. They can be illegal
  2. You might need a prescription
  3. They are drugs, not supplements
  4. They have quite different effects on people
  5. Some of them are VERY strong
  6. Lack of long-term benefits
  7. Addiction might be a problem
  8. They can be risky to take

Yes, that’s quite contrary to nootropics, which are most of them side-effects free.

So, stick to the best nootropics and nootropic supplements. You can thank us later.