Alpha Brain Review: Benefits, Side Effects & Usage

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• Fact Checked By: Spela Bednjanic, B.A. In Psychology

Alpha Brain

Product Name: Alpha Brain

Product Description: Alpha Brain is a dietary supplement for focus and cognition.

Brand: Onnit


Alpha BRAIN is a nootropic supplement that can boost focus, improve memory, and overall cognition. But does it work? Read my full review.



  • It has clinically proven results
  • It contains effective nootropics


  • Some ingredients are under-researched
  • You can experience adverse side effects

Table of Contents

Did you hear about Alpha BRAIN and its benefits? Do you want to know if this is a supplement for you?
In this review, we will cover all the important topics about this nootropic supplement. We’ll talk about its benefits, side effects, dosages, and where to buy it.
I will also share my experience with Alpha BRAIN.
At the end of the review, you will be able to decide whether this nootropic is right for you or not.

Alpha Brain review

What Is Alpha BRAIN?

Alpha BRAIN is a dietary supplement that helps support cognitive functions. It is a supplement that promotes:

  • Memory
  • Focus
  • Mental speed
  • Flow state

Alpha BRAIN helps with reasoning, problem-solving, remembering important things, and long-lasting focus. 

Since its market debut in 2011, customers bought over 1 million Alpha BRAIN bottles.

I came across this dietary supplement in 2015. Since its complex formula fascinated me, I decided to study it in detail.

Let’s check it out.

Alpha BRAIN Ingredients

Alpha BRAIN’s formula contains 12 nootropics. The formula is gluten- and caffeine-free.

Here is the Onnit Alpha Brain ingredients list: 

  • L-Tyrosine
  • L-Theanine
  • Oat straw extract
  • Vitamin B6
  • Phosphatidylserine
  • Cat’s Claw extract
  • Alpha-GPC
  • Bacopa Monnieri
  • Huperzine A
  • L-Leucine
  • Vinpocetine
  • Pterostilbene

Alpha Brain Ingredients, aplha brain

Ingredients are part of three blends:

  • Onnit Flow Blend
  • Onnit Focus Blend
  • Onnit Fuel Blend

Let’s  learn more about them. 

Vitamin B6

Vitamin B6 produces necessary coenzyme in the body. [1]

Cat’s Claw Extract

Cat’s Claw (Uncaria Tomentos) is an anti-inflammatory Amazonian vine. It helps with fatigue syndromes. [2]

Onnit Flow Blend, 650 mg

Flow Blend contains four of the mentioned nootropics.


L-Tyrosine is an amino acid that improves cognition during acute stressors, enhances our working memory and well-being. [3] It is beneficial for people who suffer from stress. 


L-Theanine is an amino acid found in green tea. It is a relaxing agent that reduces stress and increases alertness. [4] I often combine it with caffeine for simultaneous effects. [5]

Oat straw extract

Oat straw is a compound that promotes cognitive function. Anecdotal evidence shows Oat straw improving mood and boosting brain function. We lack studies that would confirm many of the anecdotal benefits. [6]


Phosphatidylserine is an ingredient that is vital for cognitive function. Supplementing it shows positive effects on memory and mental capability. [7] This amino acid can slow down cognitive decline.

Focus Blend, 240 mg

Focus blend contains three compounds.

Alpha GPC

Alpha GPC is a choline-containing compound that improves memory and decreases cognitive decline. [8] Athletes use this precursor to acetylcholine to enhance power output. [9

Bacopa Monnieri extract

Bacopa Monnieri is an adaptogen herb that improves cognition and memory. [10] Using this adaptogen can decrease anxiety. [11]

Huperzine-A (Huperzia Serrata)

Huperzine-A is a compound that belongs to the cholinergic class of molecules. It slows down cognitive decline in the elderly. [12] By inhibiting an enzyme, it increases the production of acetylcholine in the brain.

Onnit Fuel Blend, 65 mg

Onnit Fuel blend contains three compounds.


Leucine is the primary BCAA. It promotes muscle gain, but it possesses no nootropic benefits. [13]


Vinpocetine is an alkaloid from the periwinkle plant. Supplementing Vinpocetine increases the blood flow to the brain. [14]


Pterostilbene is a methylated stilbene molecule that boosts cognition, reduces cholesterol and glucose. [15]

We just covered Alpha Brain nutrition facts. Now let’s check out my Alpha BRAIN experience. 

Alpha BRAIN Review

The Alpha BRAIN founder once said: “Alpha BRAIN works the first time you try it.”

Since I was eager to try it out, I immediately ordered a 90-capsule bottle.

Alpha Brain Ingredients

Week 1

I stopped taking other nootropics a week before I started supplementing Alpha BRAIN.

I took two Alpha Brain pills on the first test day. I took them after breakfast in the morning. 30 minutes after, I became more focused. I felt a mild energy push, which surprised me.

I felt more focused and motivated for about 2-3 hours. My mood didn’t change in this period.

Not bad for the first day.

I continued taking two capsules per day. Twice I took them on an empty stomach and other times after breakfast. 

I experienced the results on most days. I felt more focused, I had more and energy and motivation.

Week 2

I continued taking the capsules for another week. I even tried three Alpha BRAIN capsules one day, but the effects stayed the same.

During the 2-week test period, I experienced no side effects. But that was not the case for my team members. Two of them felt sick when they took three capsules. We are yet to understand the exact cause of sickness. 

Nontheless, the Alpha BRAIN effects positively surprised us.

To sum it up, my experience with Alpha BRAIN was positive. Based on my experience, it can boost your cognition, focus and help with processing speed.

Now let’s talk about the optimal dosage and potential side effects. 

Alpha BRAIN Dosage

The recommended daily dosage of Alpha Brain is two capsules per day.

By taking two capsules, you will get all the promised Alpha BRAIN benefits.

But if you take more than two capsules, you can suffer from side effects.

When to take Alpha BRAIN?

I recommend taking Alpha Brain in the morning before or with your breakfast.

Alpha BRAIN Benefits

What benefits Alpha Brain pills bring? Alpha BRAIN supports brain functions such as memory, focus, and mental speed.

This supplement improves cognitive performance and productivity.

And how long does Alpha Brain effects last?

Alpha BRAIN effects last from two to four hours. I felt more focused for about three hours on most days.

Alpha BRAIN Side Effects

Nootropics are, by definition, side-effects free. But is that the case for Alpha BRAIN?

I experienced no adverse side effects during my Alpha BRAIN test. But that was not the case for my team.

Two team members experienced stomach pain and a headache during the test.

Nevertheless, Alpha BRAIN is a safe supplement. To avoid side effects, you need to follow the brands’ recommendation.

Can You Build Up A Tolerance To Alpha BRAIN?

There is no evidence that you can build up a tolerance. Even so, I recommend you weekly cycle the supplement. You can follow my 5-2 cycle formula. Take nootropics for 5 days in a row and take 2 days off. 

This is my honest recommendation to avoid the risks of side effects or tolerance.

Alpha BRAIN Reviews & Feedbacks

What do Alpha BRAIN users think of this supplement? I checked over 100 comments on different blogs, Amazon, and Onnit’s website.

I discovered many interesting reviews. Among others, I found over 450 reviews on the Alpha BRAIN official store. And the average score is over 4.2/5.


Here are I share two exciting comments that I agree with: 

 “I liked Alpha after the first few weeks but i figured it wasnt worth it. After a month and a half of using it i started to notice major differences in my focus, motivation, and overall cognitive function. TOTALLY WORTH IT!”

“Ive been on this for a few months now, feels like w-d40 in my brain, able to recall information i would think is forgotten from months ago. Less of that gimme a minute to remember, transitions between thoughts are smoother. Definitely happy with my purchase. Would recommend to anyone”

Where to Buy Alpha BRAIN? 

To buy Alpha BRAIN, click on the button for the lowest possible price: 

The price varies based on the number of pills you order, but the standard 60ct costs around $50. 

Use code YOURINCEPTION for a special 10% discount. 


Does Alpha Brain Work? Yes, Alpha Brain improves your cognitive performance. But there are better nootropic stacks available on the market.

There are three complaints I have about this nootropic stack:

  • Its formula lacks a few effective nootropics
  • My team experienced adverse side effects
  • It contains three proprietary blends

Apart from that, Alpha BRAIN is a supplement worth trying.

But if you want to check our top-rated nootropics, click on the button: 


1. Banderet, L.E. and Lieberman, H.R. (1989). Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Research Bulletin, 22(4), pp.759–762.

2. Higashiyama, Akiko, et al. “Effects of L-Theanine on Attention and Reaction Time Response.” Journal of Functional Foods, vol. 3, no. 3, July 2011, pp. 171–178, 10.1016/j.jff.2011.03.009.

Banderet, Louis E., and Harris R. Lieberman. “Treatment with Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans.” Brain Research Bulletin, vol. 22, no. 4, Apr. 1989, pp. 759–762, 10.1016/0361-9230(89)90096-8. Accessed 23 July 2019.

3. Frank, Kurtis, et al. “Theanine Research Analysis.”, 20 Jan. 2020,

4. Moccetti, T, et al. “Bioactivity-Based Development of a Wild Green Oat (Avena Sativa L.) Extract in Support of Mental Health Disorders.” Zeitschrift Für Phytotherapie, vol. 27, no. S 1, 23 Nov. 2006, 10.1055/s-2006-954926. Accessed 9 Dec. 2020.

5. Kato-Kataoka, Akito, et al. “Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints.” Journal of Clinical Biochemistry and Nutrition, vol. 47, no. 3, 2010, pp. 246–255,, 10.3164/jcbn.10-62. Accessed 8 Jan. 2020.

6. Frank, Kurtis, et al. “Vitamin B₆ Research Analysis.”, 27 Jan. 2020, Accessed 9 Dec. 2020.

7. Sheng, Y., et al. “Enhanced DNA Repair, Immune Function and Reduced Toxicity of C-MED-100, a Novel Aqueous Extract from Uncaria Tomentosa.” Journal of Ethnopharmacology, vol. 69, no. 2, 1 Feb. 2000, pp. 115–126,, 10.1016/s0378-8741(99)00070-7. Accessed 9 Dec. 2020.

8. De Jesus Moreno Moreno, Maria. “Cognitive Improvement in Mild to Moderate Alzheimer’s Dementia after Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.” Clinical Therapeutics, vol. 25, no. 1, 1 Jan. 2003, pp. 178–193,, 10.1016/s0149-2918(03)90023-3.

9. Ziegenfuss, Tim, et al. “Acute Supplementation with Alpha-Glycerylphosphorylcholine Augments Growth Hormone Response to, and Peak Force Production during, Resistance Exercise.” Journal of the International Society of Sports Nutrition, vol. 5, no. S1, Sept. 2008, 10.1186/1550-2783-5-s1-p15. Accessed 9 Dec. 2020.

10. Calabrese, Carlo, et al. “Effects of a Standardized Bacopa Monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial.” The Journal of Alternative and Complementary Medicine, vol. 14, no. 6, July 2008, pp. 707–713,, 10.1089/acm.2008.0018.

11. C., Stough, et al. “The Chronic Effects of an Extract of Bacopa Monniera (Brahmi) on Cognitive Function in Healthy Human Subjects.” Psychopharmacology, vol. 156, no. 4, 1 Aug. 2001, pp. 481–484,, 10.1007/s002130100815. Accessed 7 May 2019.

12. Ha, Giang T., et al. “Huperzine A as Potential Treatment of Alzheimer’s Disease: An Assessment on Chemistry, Pharmacology, and Clinical Studies.” Chemistry & Biodiversity, vol. 8, no. 7, July 2011, pp. 1189–1204, 10.1002/cbdv.201000269. Accessed 19 Mar. 2020.

13. Mero, Antti. “Leucine Supplementation and Intensive Training.” Sports Medicine, vol. 27, no. 6, 1999, pp. 347–358, 10.2165/00007256-199927060-00001. Accessed 19 Aug. 2019.

14. Subhan, Z., and I. Hindmarch. “Psychopharmacological Effects of Vinpocetine in Normal Healthy Volunteers.” European Journal of Clinical Pharmacology, vol. 28, no. 5, 1985, pp. 567–571, 10.1007/bf00544068. Accessed 11 Dec. 2019.

15. Riche, Daniel M., et al. “Analysis of Safety from a Human Clinical Trial with Pterostilbene.” Journal of Toxicology, vol. 2013, 2013, p. 463595,, 10.1155/2013/463595. Accessed 9 Dec. 2020.

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