PHOSPHATIDYLSERINE (500 MG)
Phosphatidylserine, or PS, is a compound similar to a dietary fat which is highly prevalent in human neural tissue. It can be synthesized as well as consumed through the diet, but further benefits can be gained through supplementation.
It is vital for cognitive function, but is not necessarily needed as the body synthesizes it. However, Phosphatidylserine (PS) supplementation in older individuals seems to improve memory and cognitive capacity.
SULBUTIAMINE (400 MG)
Sulbutiamine is a highly bioavailable form of Vitamin B1 that facilitates the stimulation of the neurotransmitters glutamate and dopamine and increases communication between neurons in the brain. Sulbutiamine can drastically increase motivation, cognitive function, and attention levels.
TeaCrine® (100 MG)
TeaCrine® is a patent-pending compound containing pure teacrine which has molecular similarities to caffeine. However, unlike caffeine, TeaCrine® provides energy boosting effects without the jitters, the crash and the habituation that often accompany caffeine consumption.
I’ve read about TeaCrine before – I think we still lack some research, but there seems to be a high potential in TeaCrine.
ALPHA-GPC (300 MG)
ALPHA-GPC is a water-soluble chemical that improves signal transmission within the brain and directly increases the synthesis and secretion of acetylcholine. Raising the levels of acetylcholine causes the brain to rapidly form more connections and increases the speed at which the brain can process new and existing information.
Several nootropics include Alpha-GPC and there is a lot of research proving the effects of it. I’m happy AZOTH includes it in the formula in a relatively high-dose.
HUPERZINE A (1%) (10 MCG)
Huperzine A incites neurons to make new connections at an extremely rapid rate, thus accelerating learning speed and capacity to superhuman levels.
L-TYROSINE (500 MG)
L-TYROSINE increases brain neurotransmitter concentrations and suppresses rises in cortisol and norepinephrine depletion. This has the effect of severely reducing stress during times of high-pressure, increasing reaction time, and augmenting awareness and cognition during periods of intense sleep or nutrient deprivation.
HORDENINE HCL (50 MG)
Hordenine creates a hormonally balanced neurological environment with excellent alertness, very fast response time to stimulus, and the mental acuity to focus upon work for long stretches of time without drifting into a fog.
Ashwagandha Root (500 MG)
As a powerful anti-oxidant, Ashwagandha promotes immune protection and is used to significantly reduce performance anxiety before major life events.
Besides, Ashwagandha can improve physical performance as well as reduce LDL cholesterol.
Bioperine™ (10 MG)
Bioperine is the only product sourced out of piperine to obtain a patented status for its ability to increase the bioavailability of nutritional compounds. Taking Bioperine increases the likelihood that the ingredients you are ingesting are actually being absorbed by your body.
WHAT I LIKE IN THE FORMULA
There are several great ingredients in this formula and what I really like is that they are not underdosed as it usually happens with nootropic stacks.
Also, the formula contains a lot of Alpha-GPC and Phosphatidylserine (PS).
Alpha-GPC is used to increase acetylcholine availability which actually means brains have a better capability to digest and comprehend information. Saying it differently, Alpha-GPC is more or less a must if you want to dramatically improve your memory.
PS, on the other hand, is a great cognitive enhancer. You can see it in this study (https://www.ncbi.nlm.nih.gov/pubmed/22017963) that only 2 weeks of taking PS and your calculation speed will improve.
WHAT I’M NOT SO SURE ABOUT
If I compare AZOTH to my favorite nootropic stack Mind Lab Pro, I notice some disadvantages in the formula.
For example, I heard a lot about Hordenine and the potential side-effects of taking it.
Also, I miss ingredients that would improve long-term memory function such as Bacopa monnieri.
I’d also consider changing Ashwagandha with Rhodiola rosea, but since I’m not a doctor or a biologist, let’s leave this to the experts.
In general, the stack has a medium-to-high dose of each ingredient, which could cause some side-effects in some people. Therefore, cycling it (3 weeks on, 1 week off) is definitely useful.